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Author
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Topic: Vioxx vs. Celebrex
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Barry
unregistered
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posted November 10, 2002 12:02 PM
Suemsj:
Fear not. I have been on Vioxx for 4 years with NO side effects. And I DO have a sensitive stomach. It works much better than Celebrex. MUCH. Try it!
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suemsj
First time visitor Posts: 1
Registered: Nov 2002
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posted November 06, 2002 02:34 PM
 
my doctor gave me vioxx because of painful periods. ive also been on prevacid for 3 months for stomach problems. im afraid to take the vioxx. has anyone taken vioxx who has ulcers and stomach trouble?
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Jadamson
unregistered
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posted October 02, 2002 02:19 PM
I am an avid triathlete and have lived with AS for over 20 years and have tried just about all the medications available including Vioxx and Celebrex. Celebrex is the only medication that has kept me training and competing with little or no pain. In a given week I will swim 2-3 miles, bike 100 miles+, and run 20-30 miles and since switching to Celebrex rarely have flare ups or respitory infections. On Vioxx I found myself cutting back on my running due to pain in the hip and seemed to always catch colds. I also found that my heartrate during excercise was 10 beats per minute higher than it usually was. Now I just need Celebrex to sponsor me and supply me with a new bike! I think intense excercise is one way to stay on top of this desease.
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Kathy
Registered Visitor Posts: 60
Registered: Jun 2002
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posted September 28, 2002 01:15 PM
I'm taking 20 mg of Bextra daily too. I was in so much pain, and had a lot of finger and knee swelling, so my doctor decided not to mess around with a low dose. I know Vioxx works great for a lot of people, and I have always wondered why it doesn't work well for me too. Anyway, I'm just happy that the Bextra is available and that it works so well. Nothing offers 100% pain relief, but the alternative is worse! I'm still taking Methotrexate and Presnisone. My doctor is slowly weaning me off Pred, but has increased the Methotrexate -- he says that the increased MTX should compensate for the withdrawl of the Prednisone. I don't quite understand how that works, as they are completely different drugs, but I am trusting that he knows what he's doing.
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Kathleen
Registered Visitor Posts: 58
Registered: Aug 2002
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posted September 27, 2002 06:34 PM
I've been on Bextra for 3 months and it helps a lot. I still have pain and stiffness, but it is better than it was. The doctor prescribed 10 mg, but I started taking 20mg and it does a better job. The doctor said it was okay and a drug rep told me you can actually take 20mg twice a day for dysmenorrhea. I also have a sulfa allergy, otherwise he would have tried sulfazaline. I am not willing to use any other meds at this time since my symptoms are pretty manageable and the side effects of methotrexate and other agents are no picnic.
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Kathy
Registered Visitor Posts: 60
Registered: Jun 2002
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posted September 27, 2002 02:10 AM
Is anybody besides me taking Bextra, the newest (introduced last year) of the Cox 2 inhibitor drugs? I can't take Celebrex because of sulfa allergy, and didn't have much luck with Vioxx controlling the pain. Now that I'm taking Bextra, I feel better. But of course I suppose that could be because I'm taking it along with Methotrexate. It would be interesting to see if I continued to feel well if I switched back to Vioxx (taken along with MTX.) In any case, it took about 7 days for Bextra to kick in, and since then, it's worked pretty well. Spencer23 is right; we all have different responses to drugs, and some drugs do take a bit of time before any benefit is realized. Also, for me, Bextra has been easier on my stomach.
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sam
Registered Visitor Posts: 17
Registered: Aug 2002
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posted September 26, 2002 12:04 PM
I have been taking Celebrex for only 5 weeks but it has been fabulous. It did, however, take about 5 days before I felt substantial pain relief (my doctor told me to give it a week). Before Celebrex I took Voltarin (Diclofenac) but only lasted 1 month before intestinal problems started and pain broke through.
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stef
unregistered
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posted September 26, 2002 11:13 AM
Well, from what i've read of this discussion, celebrex is quite ineffective for AS sufferers. Well, you're right.I was on it for a year and really felt no relief at all unless it was taken with other things, and even then I experienced a lot of pain. Why I paid for that garbage for a year is beyond me. I guess it is because i only see my specialist yearly, so when i went back after a year, I told her it wasnt working. And then it was Vioxx. My savior. It really helps with managing the daily pain, but when I get a flare up, forget it. That takes numerous advils, muscle relaxants and a heating pad in conjunction to the vioxx to get some relief. But anyways, as far as celebrex goes, don't wait too long thinking that it will start working. Same goes for all the other antiinflamitories. I've been through them all, except the ones newer than vioxx. Personally, I would promote vioxx. But then again, everyone reacts different to these drugs. So if you find that the one you are taking is not what it is all cracked up to be, keep switching till you find something that works. In this day in age nobody should have to suffer such pain when there are so many things available to help it. If you try them all and none work, well, the medical community has failed you. But i do not doubt that they will eventually create something that will work. Good luck to you all 
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mikemaan
Registered Visitor Posts: 3
Registered: Dec 2001
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posted September 26, 2002 09:20 AM
BTW I am getting my Vioxx from the Fijian Islands and it's the authentic REAL thing with Merk logo and identical pill color and markings. It costs close to US$105 or FJ$210 for 100 tabs of the 25mg which includes shipping. It usually arrives within 10 days. Adjust your dollar amount and quantities using Fijian Dollars.Send a fax with your perscription and CC# and shipping info to Kavita @ Budget Pharmacy in Nadi (pronounced Nandy) Fiji. 011-679-670-2285. I found these guys while vacationing there last year. Their voice line is 011-679-670-0064. They are very nice and this is legal with scrip and a great money saver. I have done this three times this year without a hitch. They don't have a web site they don't advertise it's just a little pharmacy I found in Nadi.
-Mike
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Kurt
unregistered
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posted September 25, 2002 06:16 PM
mmahaney, have to agree we are all guinea pigs these days but hopefully the next generation will benefit - namely my kid.
Anyway, has anyone found Vioxx making them tired? Celebrex gives me bad diarhea (sp?)
But both worked well for me, Vioxx better but the the tiredness and occassional tinitus drove me to a change. Kurt
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mmahaney@sprint.ca
unregistered
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posted September 23, 2002 03:32 PM
vioxx vs celebrex vs arthrotec. have just finished 1 month of arthrotec, and previously took celebrex and before the scare, vioxx. will be going back to vioxx shortly as it was the most effective and as long as I take my 81mg aspirin in the a.m. I should be just fine. sometimes i think we are nothing but guinea pigs for the drug companies haha good luck all
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KENK
Registered Visitor Posts: 6
Registered: Jul 2002
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posted August 01, 2002 09:37 AM
TRIED TOTAL OF 5 VIOXX HOPING THIS WOULD BE
SUFFICIENT TO BREAK THE NECK PAIN FLARE. IT DIDN'T. UNTIL I GET SOMETHING WORKED OUT WITH MY INSURANCE, I'M TOO STUBBORN TO PAY $5
EACH FOR 25mg VIOXX ALTHOUGH THEY DID SEEM TO BE MUCH MORE EFFECTIVE THAN CELEBREX.AS AN EXPERIMENT, I STOPPED AT THE DRUGSTORE THIS MORNING AN PRUCHASED NAPROXEN SODIUM AND AM GOING TO TRY 220mg TWICE PER DAY IN LIEU OF RESUMING THE CELEBREX. IT'S BEEN QUITE A FEW YEARS SINCE I TOOK PRESCRIPTION NAPROSYN, BUT I RECALL IT WORKED PRETTY WELL. I'LL POST RESULTS AFTER TAKING NAPROXYN FOR A FEW DAYS.
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weekendatbernies
unregistered
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posted August 01, 2002 05:28 AM
Interesting how the GP's vary in opinion. Mine told me that neither would be immediately effective for at least a couple of weeks. That being said and to be a little redundant, I found Vioxx to work almost immediately while the Celebrex took a couple of days to kick in. I noticed that the effectiveness of the NSAIDS that I have taken (Vioxx, Arthrotec, Mobicox)has declined with steady use, and I typically switch after a couple of months. Has anyone else found this or am I once again the freak of the litter?
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Amber UK
unregistered
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posted August 01, 2002 03:30 AM
Hi,I've just taken my first (25mg) dose of vioxx. I had particulary bad pain in my feet and ankles last night, and I noticed relief within 2 hours of taking it, and I also slept quite well thru the night, with much less stiffness on waking. I cant compare it with anything, as this is the first drug I've been perscribed.
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Tammy
Registered Visitor Posts: 25
Registered: Jul 2002
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posted July 31, 2002 05:18 AM
I was on vioxx and my Dr. said it would take up to a week to feel the full effects. I felt a difference in pain level after a few days. I cannot take celebrex because I'm allergic to sulpha drugs. My insurance had to approve the vioxx, but it was worth the short wait.The only thing that worries me is stomach bleeding can occur,but I guess all drugs have some possible side effects.
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KENK
Registered Visitor Posts: 6
Registered: Jul 2002
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posted July 30, 2002 09:01 AM
I HAVE SUFFERED WITH AS FOR 18 YEARS WITH FLARE-UPS APROX EVERY 3 MONTHS. ORIGINALLY MOST SYMPTOMS WERE SEVERE HIP PAIN WHICH LASTED A FEW DAYS TO A WEEK. RHEUMATOLOGIST RICHARD RUBIN IN HOUSTON PRESCRIBED KETOPROPHEN AND CYTOTEC WHICH WORKED PRETTY WELL FOR THREE YEARS OR SO. HE THEN SWITCHED TO ARTHROTEC WHICH ALSO WORKED WELL.SIX MONTHS AGO I BEGAN TAKING CELEBREX 200MG
TWICE DAILY. I HAVE RECENTLY BEEN HAVING SEVERE FLARES OF NECK PAIN AND VIRTUAL IMMOBILITY LASTING UP TO THREE WEEKS. LAST FRIDAY I BORROWED 2 VIOXX FROM A FRIEND AND COULD FEEL BENEFIT WITHING TWO HOURS AND I WAS MUCH INPROVED THE NEXT DAY WHEN I TOOK THE LAST VIOXX. I CALLED MY GP AND ASKED HIM TO WRITE ME A SCRIP FOR VIOXX, WHICH HE CALLED IN TO MY PHARMACY, BUT MY INSURANCE CARRIER REJECTED IT. I HAD GONE BACK TO CELEBREX AND THE PAIN RETURNED. I PAID $5 PER PILL FOR THREE 25MG VIOXX YESTERDAY AFTERNOON AND, AGAIN, THE RELIEF WAS EVIDENT WITHING A COUPLE OF HOURS AND I GOT A MUCH BETTER NIGHTS SLEEP LAST NIGHT. SUMMARY: FOR ME, 58 YEAR OLD MALE WITH SEVERE NECK PAIN FLARES, VIOXX SEEMS TO WORK MUCH BETTER, AT LEAST SHORT TERM. IF ANYONE IS INTERESTED, I WILL POST FURTHER RESULTS AFTER A COUPLE OF MONTHS.
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Spenser23
Registered Visitor Posts: 156
Registered: Nov 2001
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posted December 11, 2001 09:21 PM
No problem, Spanky28, I don't mind being second guessed ... but only when I've screwed up, okay? lol.Seriously, thanks for the help. I try to make my posts accurate, but I'm only human and sometimes I can mis-state a fact. Take Care.
Spenser23@aol.com
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spanky28
unregistered
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posted December 11, 2001 12:23 PM
Spenser23, sorry about the spelling error.
I realize that you didn't say that the longer you take it the better it works, but I think that's how people will view it.
I hope I didn't come across as second guessing you.... I just wanted to let you know that those are "shorter-term" NSAIDS. (so to speak)
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Spenser23
Registered Visitor Posts: 156
Registered: Nov 2001
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posted December 11, 2001 10:21 AM
Hi Spanky. First off, my screen name is SpenSer23. (this is to avoid confusion with the person here with the screen name, Spencer.)Secondly, I did not say that the drugs work better the longer you take them. That is quite a different thing. But, I did go back and double check, and although those sales reps of yours may be exaggerating a bit, you are right, Vioxx and Celebrex are different than other NSAIDS as far as the length of time in which they reach a level of effectiveness. They are much quicker to achieve relief than other NSAIDS. I stand corrected on that point. However ... Celebrex can still take as long as a couple of days to reach effectiveness while Vioxx claims to reach an effective level of relief within hours. So i stand by my opinion that taking Celebrex for only a couple days did not give it enough of a chance. Thanks for the correction. I apologize for mis-speaking.
Spenser23@aol.com
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spanky28
unregistered
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posted December 11, 2001 06:57 AM
This is in response to Spencer 23. When taking NSAID's such as Vioxx and Celebrex at least those 2.....they do NOT work better the longer you take them. I realize that some medications may take that long to work. But as far as Vioxx it is strictly a 24hour dosing drug. You should feel relief with in 2 hours and peak around 10-12 hours and level off after that. There is no more benefit to taking it weeks or months.
So in tha case of those NSAIDS you SHOULD feel immediate relief. Just wanted to add my 2 cents. I work in a clinic where I see drug reps on a daily basis and asked them about these NSAID's.
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mikemaan
Registered Visitor Posts: 3
Registered: Dec 2001
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posted December 08, 2001 10:26 PM
I compared Celebrex to my experience with Vioxx. The first day I took Vioxx I felt relief within 4 hours. I thought that since Celebrex was the same type of drug (Cox-2 inhibitor) that it would work the same. So I guess you a suggesting I give it another try?
-Mike
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Spenser23
Registered Visitor Posts: 156
Registered: Nov 2001
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posted December 08, 2001 09:43 PM
Hi Mikemaan. Differences in individual body chemistry means some drugs will work better for you than others, and therefore, your experience with a drug may be totally opposite from mine. That being said, I believe the problem, (and a LOT of people seem to have this same problem), is that you think that you can take a med like Celebrex and get immediate results. That is not how these kinds of meds work. It is not like taking an antacid for a stomach ache. These meds usually take weeks (and sometimes months), to get up to their full level of effectiveness. They need time to build up in your bloodstream, and once they kick in, you need to keep taking them to maintain the proper level in your bloodstream. In other words, you can't simply take them when you feel bad, or stop taking them when you feel good. Taking Celebrex for only three days was simply to short a period to measure whether ot not it would be an effective drug for you. I hope this helps.
Spenser23@aol.com
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Tinman
Registered Visitor Posts: 20
Registered: Nov 2001
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posted December 08, 2001 06:21 PM
Hello Mikemaan,
I'm currently taking Vioxx and Remicade. The results have been great so far. Prior to the Vioxx my Rheummy prescribed Celebrex which actually brought on a flare up. After stopping the Celebrex the flare up went away. That was just my experience and other peoples will probably vary.
There is also a comparison on the other thread Doxicycline ( sp?)
I hope this helps. Tinman
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mikemaan
Registered Visitor Posts: 3
Registered: Dec 2001
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posted December 08, 2001 04:19 PM
Before my recent AS diagnosis I had been on Vioxx 25-50mg/day perscribed by an anesthesiologist. When I went to see my Rhummey for the first time he suggested I switch to Celebrex because he said it had lower complications. I tried it for a couple of days with no results. So I flipped back to Vioxx and the pain subsided again. Any comments or suggestions will be much appreciated. I apologise in advance if this has been debated in the past, I'm a newbie. :-)
-Mike
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